Thoracic diseases requiring thoracoscopic surgery
Conditions
Interventions
Experimental group (Group L):Slow intravenous injection of 1.5 mg/kg of lidocaine over 10 min before induction and continuous pumping of lidocaine at a rate of 2.0 mg/kg/h after intubation until the e
Control group (Group N):The same volume of saline was given as placebo.
Sponsors
Tongling People's Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 100 Years
Inclusion criteria
Inclusion criteria: Patients with ASA classification I-III, age >= 18 years, and proposed elective transvideo-assisted thoracoscopic surgery under general anesthesia.
Exclusion criteria
Exclusion criteria: (1) Severe hepatic, renal and endocrine abnormalities; (2) Neuropsychiatric disorders, neuromuscular disorders; (3) Allergy to amide local anesthetics; (4) Severe cardiac disease (severe arrhythmia, Adame-Strokes syndrome, III degree AV block, preexcitation syndrome, congestive heart failure, etc.) prior to the operation; (5) Electrolyte disorders, epileptic seizures, pregnancy or breastfeeding; (6) chronic lung diseases (pulmonary cystic fibrosis, bronchial dysplasia, pulmonary hypertension, chronic obstructive pulmonary disease, etc.) or abnormal pulmonary function tests; (7) BMI >= 30 kg/m^2; (8) preoperative inspiratory pulse oximetry of less than 95% due to neocoronary pneumonitis, etc.; and (9) refusal to participate in the trial or to sign the test by the patients themselves or their families.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Quality of Recovery (QoR-40) score at 24h postoperatively; | — |
Secondary
| Measure | Time frame |
|---|---|
| Incidence of PPCs within 7 days of surgery;Hemodynamic changes in patients after induction and intubation;VAS PAIN SCORE; | — |
Countries
China
Contacts
Public ContactZhu Mudan
Tongling People's Hospital
Outcome results
None listed