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A Study on the Evaluation of Retinal Microcirculation and Structural Changes in Myopic Patients with Ocular Hypertension

The Evaluation of Retinal Microcirculation and Structural Changes in Myopic Patients with Ocular Hypertension Using Optical Coherence Tomography Angiography

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2500095851
Enrollment
Unknown
Registered
2025-01-14
Start date
2025-01-20
Completion date
Unknown
Last updated
2025-01-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Ocular hypertension

Interventions

Simple myopia group:None
Myopia with ocular hypertension group:None

Sponsors

Tianjin Medical University Eye Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
6 Years to 70 Years

Inclusion criteria

Inclusion criteria: 1.Simple myopia group: 6y=0.8; 4.Simple myopia group: intraocular pressure 21 mmHg;

Exclusion criteria

Exclusion criteria: 1.History of combined systemic diseases such as hypertension, diabetes and hyperthyroidism; 2.Previous history of intraocular surgery or combined retinal detachment, retinal vascular disease, and other intraocular diseases; 3.Previous history of ocular trauma, involvement of visual pathways, and secondary myopia; 4.Unable to cooperate with visual field examination or unreliable visual field examination results (unreliable visual field examination results include fixation loss>20%, false positive rate and false negative rate >= 15%); 5.The signal strength of OCTA inspection < 6; 6.Myopia with high intraocular pressure group: exclusion criteria are the same as those for the simple myopia group;

Design outcomes

Primary

MeasureTime frame
Density of blood vessels in and around the optic disc;Density of blood vessels in and around the macula;The area of blood flow in and around the optic disc;Area of blood flow in and around the macula;Retinal ganglion cell layer thickness ...;Best corrected visual acuity;Corneal biomechanical parameters;

Secondary

MeasureTime frame
Retinal nerve fiber layer thickness;Retinal ganglion cell layer thickness;

Countries

China

Contacts

Public ContactAihua Liu

Tianjin Medical University Eye Hospital

liuaihua8136@126.com+86 22 86428705

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026