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High-voltage pulsed radiofrequency combined with tolerable radiofrequency thermocoagulation for post-herpetic neuralgia: a single-center, prospective, randomized, single-blind, controlled study

High-voltage pulsed radiofrequency combined with tolerable radiofrequency thermocoagulation for post-herpetic neuralgia: a single-center, prospective, randomized, single-blind, controlled study

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500095846
Enrollment
Unknown
Registered
2025-01-14
Start date
2025-01-31
Completion date
Unknown
Last updated
2025-01-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

postherpetic neuralgia

Interventions

Test group:On the basis of the original high-voltage pulsed radio frequency, the combination can withstand radio frequency thermoagulation.
Control group:Simple high-voltage pulse radio frequency technique

Sponsors

Huzhou Central Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
35 Years to 90 Years

Inclusion criteria

Inclusion criteria: (1) PHN (T1-T12) caused by thoracic spinal nerves; (2) history of herpes zoster for more than 1 month; (3) persistent severe pain with/without localized cutaneous hyperalgesia, and sensory abnormality even after complete healing of the cutaneous lesion; (4) failure to control the pain with standard medication (antiepileptic drugs, antidepressants, opioids) or physical therapy recommended by the International Association for the Study of Pain; (5 ) Those with a 24-hour visual analog score of 5 or more; (6) Those who received pulsed radiofrequency therapy for the first time, and subjects voluntarily participated in this study and signed an informed consent form.

Exclusion criteria

Exclusion criteria: (1) Have a history of malignant tumors and are currently in anti-tumor treatment; (2) History of systemic immune diseases; (3) incomplete follow-up information; (4) Have received other interventional treatments before or during follow-up; (5) Mental or psychological disorders.

Design outcomes

Primary

MeasureTime frame
Visual Analogue Scale;

Secondary

MeasureTime frame
Assens Insomnia Scale;Hamilton Anxiety Scale;Patient Health Questionnaire (PHQ-9);

Countries

China

Contacts

Public ContactYingfeng He

Huzhou Central Hospital

19857278575@163.com+86 198 5727 8575

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026