ischemic stroke
Conditions
Interventions
Dual task training group:the dual task training
Control group:routine rehabilitation treatment
Dual-task training with blood flow restriction group:the dual-task training with blood flow restriction
Sponsors
The First People’s Hospital of Lianyungang
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1. Diagnosed with ischemic stroke according to the diagnostic criteria outlined in the 2019 edition of the Chinese Guidelines for the Diagnosis of Various Cerebrovascular Diseases and confirmed by CT or MRI; 2. relatively stable condition, no consciousness disorders, and able to cooperate with examinations and treatment; 3. aged 18–70 years; 4. presence of impairment in at least one cognitive domain, resulting in a decline in daily living abilities, with a Montreal Cognitive Assessment (MoCA) score = Grade 3; 7. Brunnstrom stage of the affected lower limb in stages III–V; 8. signed informed consent form.
Exclusion criteria
Exclusion criteria: 1. Severe soft tissue injury, fracture, or peripheral vascular disease; 2. Coagulation disorders or active bleeding, with lower limb thrombosis confirmed by Doppler ultrasound; 3. Unstable vital signs (e.g., systolic blood pressure 220 mmHg, heart rate 100 bpm, peripheral oxygen saturation =38.5°C); 4. Severe hepatic, pulmonary, and/or renal dysfunction; 5. Lower limb fracture or other factors that hinder the completion of motor training; 6. Concomitant acute coronary syndrome or severe arrhythmia; 7. Severe cognitive impairment.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Assessment of motor function;Cognitive function assessment; | — |
Secondary
| Measure | Time frame |
|---|---|
| Magnetic resonance diffusion tensor Imaging (DTI) metrics;Serum neurotrophic factors and inflammatory cytokines; | — |
Countries
China
Contacts
Public ContactZhou Fang
The First People’s Hospital of Lianyungang
Outcome results
None listed