Cirrhotic patients undergoing TIPS
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Cirrhosis from various etiologies is confirmed through clinical data combined with imaging or liver biopsy. 2. Cirrhotic patients undergo TIPS procedure based on appropriate indications, such as variceal bleeding and refractory ascites. 3.Patients have preoperative abdominal CT imaging available at the treating hospital to assess sarcopenia.
Exclusion criteria
Exclusion criteria: 1. Age under 18 years. 2. Uncertain cirrhosis diagnosis or undergoing TIPS for other reasons, such as Budd-Chiari syndrome or idiopathic portal hypertension. 3. Previously received TIPS, with current procedure performed due to stent occlusion. 4. Poor quality abdominal CT imaging, lack of third lumbar vertebra level imaging, absence of dynamic CT images (e.g., only film available), or preoperative CT performed more than 3 months before surgery. 5. Presence of neurological or psychiatric disorders, or current use of anti-anxiety or antidepressant medications interfering with postoperative HE assessment. 6. Advanced liver cancer exceeding Milan criteria, other systemic malignancies, or severe chronic diseases (e.g., stage 4 or higher chronic kidney disease) impacting patient prognosis. 7. Incomplete or missing clinical data. 8. Loss to follow-up within 3 months. 9. Prospective cohort patients who declined to sign informed consent or requested withdrawal during the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Sarcopenia; | — |
Secondary
| Measure | Time frame |
|---|---|
| discriminability;Calibration degree;Clinical utility; | — |
Countries
China
Contacts
Xi'an Jiaotong University Second Affiliated Hospital