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Metformin improves reproductive outcomes in women with endometriosis in a prospective study

Metformin improves reproductive outcomes in women with endometriosis in a prospective study

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500095839
Enrollment
Unknown
Registered
2025-01-14
Start date
2025-01-16
Completion date
Unknown
Last updated
2025-01-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

endometriosis

Interventions

group 1:Metformin pretreatment for 3 months before ovulation stimulation
group 2:No metformin pretreatment for 3 months before ovulation stimulation

Sponsors

Shanghai First Maternity and Infant Hospital
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
20 Years to 40 Years

Inclusion criteria

Inclusion criteria: Women younger than 40 years of age, all diagnosed with ovarian endometriosis under laparoscopic surgery, all women with endometriosis with one or both ovarian cysts less than 4 cm in size, and all women with an AMH greater than 1 and an FSH less than 10

Exclusion criteria

Exclusion criteria: Women who had used hormonal drugs in the 3 months prior to ovulation were excluded, as were women with uterine fibroids, endometrial polyps, uterine malformations, and hydrosalpinx.

Design outcomes

Primary

MeasureTime frame
live birth rate;

Secondary

MeasureTime frame
Duration of gonadotropin stimulation;

Countries

China

Contacts

Public ContactHe Xiaoying

Shanghai First Maternity and Infant Hospital

xiaoyinghe1262024@126.com+86 185 1651 5820

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026