Post-cesarean pain
Conditions
Interventions
Liposomal group(LB):Participants in the LB group will receive a bilateral quadratus lumbar nerve block under ultrasound guidance using bupivacaine liposomal injection (20 ml per side, 133 mg).
Ropivacaine + PCIA group(R-P):Participants in the R-P arm will receive a bilateral quadratus lumbar nerve block under ultrasound guidance using ropivacaine injection (20 mL per side, 0.375% ropivacain
PCIA group(P):Participants enrolled in group P will be managed with standard PCIA, without supplementary nerve block interventions.
Sponsors
The Affiliated Hospital of Qingdao University
Eligibility
Sex/Gender
Female
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Aged 18 and above; 2. Elective cesarean section; 3. Fetuses at term, defined as 37 to 42 weeks of gestation; 4. Individuals who provide consent to participate in this study and sign the informed consent document.
Exclusion criteria
Exclusion criteria: 1. Presence of local infection at the proposed injection site; 2. Exhibited contraindications for spinal anesthesia; 3. Known hypersensitivity to trial-related medications; 4. Significant cardiovascular or pulmonary disease; 5. Suffered from severe liver or kidney dysfunction; 6. Having a history of significant mental or other health conditions, including severe visual or auditory impairments, or an inability to communicate, which precludes assessment or examination; 7. Past medical history of neurological deficits; 8. Chronic pain conditions; 9. Current use or abuse of opioids.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The visual analogue scale pain score, evaluated during standardized movement; | — |
Secondary
| Measure | Time frame |
|---|---|
| The visual analogue scale pain score at rest;Patient self-assessment of Quality of Recovery-15 (QoR-15) scale;Postoperative acute analgesic requests;Postoperative anxiety assessment of repeat cesarean section;Subjective sleep quality;Nausea;Vomiting;Postoperative sufentanil consumption;Length of hospital stay;Single walking episode duration;Patient’s satisfaction with analgesic; | — |
Countries
China
Contacts
Public ContactWang Yanting
The Affiliated Hospital of Qingdao University
Outcome results
None listed