Inferior vena cava collapsibility index under sedation before general anesthesia can predict hypotension after Induction in elderly patients

Status

Active, not recruiting

Phases

Phase 4

Study type

Observational

Source

ChiCTR

Registry ID

ChiCTR2500095828

Enrollment

Unknown

Registered

2025-01-14

Start date

2025-02-10

Completion date

Unknown

Last updated

2025-01-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hypotension after induction of general anesthesia in elderly patients

Interventions

No need for subgroups, using own before and after controls:10° Trendelenburg position, administration of midazolam 0.05 mg/kg

Eligibility

Sex/Gender

All

Age

65 Years to 80 Years

Inclusion criteria

Inclusion criteria: (1) Age: 65-80 years old, any gender, body mass index (BMI): BMI 18-28 kg/m2; (2) American Society of Anesthesiologists (ASA) classification I-II, Mallampati airway classification I-II; (3) Patients requiring general anesthesia under tracheal intubation via gastrointestinal preparation; (4) With the ability of autonomous behavior, clear consciousness, and able to cooperate to complete the experiment; (5) Respondents agreed to participate in the study and signed an informed consent form.

Exclusion criteria

Exclusion criteria: (1) Failure to participate in the trial and refusal to sign the informed consent form; (2) ASA classification III to IV; (3) History of allergy to sedative drugs and other serious anesthetic risks; (4) Presence of major peripheral vascular disease and severe vascular disease; (5) Currently taking angiotensin-converting enzyme inhibitors or angiotensin receptor blockers; (6) Preoperative hypotension (baseline MBP less than 70 mmHg) or baseline blood pressure systolic blood pressure (SBP) greater than 160 mmHg; (7) Patients at risk of reflux aspiration; (8) Elevated intracranial pressure; (9) Unstable angina or left ventricular ejection fraction less than 40%; (10) With moderate or severe heart valve disease; (11) Implantation of a pacemaker or cardioverter.

Design outcomes

Primary

Measure	Time frame
Inferior vena cava collapsibility index(IVCCI);systolic blood pressure(SBP);diastolic blood pressure(DBP);mean arterial pressure (MAP);heart rate(HR);Maximum inferior vena cava diameter(dIVCmax);Minimum inferior vena cava diameter(dIVCmin);	—

Secondary

Measure	Time frame
age;sex;height;weight;American Society of Anesthesiologists (ASA) Health Status Classification;Have high blood pressure;Medications currently taken to treat high blood pressure;Type of surgery;	—

Countries

China

Contacts

Public ContactXiaobo Chen

Yichang Central People's Hospital, Hubei Province, China

A15871583801@163.com+86 158 7158 3801

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026