gastroenteroscopic anesthesia
Conditions
Interventions
Group S:Sufentanil combined with propofol at the 95% effective dose
Group A:Oliceridine combined with propofol at the 95% effective dose
Sponsors
The Second People's Hospital of Hefei City.
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1.aged between 18 and 65 years old (inclusive); 2.classified as ASA physical status I - II; 3. with a body mass index (BMI) ranging from 18.5 to 27.9 kg/m²; 4. undergoing painless gastrointestinal endoscopy, excluding those undergoing therapeutic procedures; 5.capable of understanding, voluntarily signing the informed consent form, and willing to comply with the requirements of the experimental protocol; 6.the expected operation time is no more than 30 minutes
Exclusion criteria
Exclusion criteria: 1.Unwilling or unable to complete the whole study; 2.Those who are allergic to or have contraindications for opioid drugs, propofol and other drugs as well as their components used in the study; 3.Severe heart, liver and kidney insufficiency; 4.Having a history of alcoholism, mental illness, pregnancy or lactation; 5.Patients with uncontrolled severe hypertension; 6.Those who are allergic to opioid drugs or have a history of abusing such drugs; 7.Patients with acute upper respiratory tract infections or intestinal obstruction.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Patient recovery time;Respiratory depression;Circulatory depression; | — |
Secondary
| Measure | Time frame |
|---|---|
| Baseline;Vital signs;Pain on intravenous injection;Nausea, vomiting and dizziness after regaining consciousness; | — |
Countries
China
Contacts
Public ContactHu Dengyun
The Second People's Hospital of Hefei City.
Outcome results
None listed