Overweight/Obesity
Conditions
Interventions
Sponsors
Reproductive Hospital Affiliated to Jiangxi University of Traditional Chinese Medicine
Eligibility
Sex/Gender
All
Age
18 Years to 35 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria for normal healthy population: (1) Normal population (18.5 = BMI = 23.9 kg/m2); (2) 18-35 years old; (3) Voluntary participation in this study and signing of informed consent. Inclusion criteria for overweight/obese patients: (1) overweight/obese (BMI = 24.0 kg/m2); (2) 18-35 years old; and (3) voluntary participation in the study and signing of informed consent.
Exclusion criteria
Exclusion criteria: Exclusion Criteria for Normal Healthy Population: (1) Those who have serious organic lesions of heart, liver, kidney, blood system or chronic diseases; (2) Those who have taken medications affecting body weight, blood glucose, blood lipids and other indicators in the last 3 months; (3) Those who are pregnant; (4) Those who have undergone weight-loss surgeries; (5) Those who are unable to perform the physical function test or answer the questionnaire questions; (6) Those who are unable to comply with the test procedures; (7) Those who are allergic to the components of the products; (8) Those who refuse to sign the informed consent form; (9) Those who have taken weight-loss or anti-anxiety and depression related drugs or received weight-loss treatment by dietitians. (7) Allergic to the ingredients of the test product; (8) Refused to sign the informed consent form; (9) Taking weight loss, anti-anxiety and depression related medication within the last 3 months or receiving weight loss treatment from a dietitian. Exclusion criteria for overweight/obese patients: (1) having serious organic lesions of the heart, liver, kidney, blood system, or chronic diseases; (2) taking medications affecting body weight, blood glucose, blood lipids, etc. in the past 3 months; (3) being pregnant; (4) undergoing weight-loss surgeries; (5) being unable to perform the physical function test or answer the questionnaires correctly; (6) not being able to comply with the test procedures; (7) being allergic to the ingredients of the test products; (8) refusing to sign the informed consent form; (9) taking weight-loss and anti-anxiety and depression related drugs or receiving weight-loss treatment by dietitians. (7) allergic to the ingredients of the test product; (8) refused to sign the informed consent form; (9) taking weight loss, anti-anxiety and depression related medication or receiving weight loss treatment from a dietitian within the last 3 months.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Weight;BMI;BFP;waist circumference;Waist-to-Hip Ratio;fasting blood sugar;glycated haemoglobin;Hamilton Depression Score;Hamilton Anxiety Score;Pittsburgh Sleep Quality Index Score;Metabolites associated with anxiety-depressive-like behaviour in faeces (gamma-aminobutyric acid, 5-hydroxytryptamine, dopamine);Stool high-throughput sequencing;Metabolome sequencing of faecal samples; | — |
Secondary
| Measure | Time frame |
|---|---|
| Obesity-related metabolites in faeces(LPS,SCFA);Liver function 5 tests;GLP-1;inflammatory factor; | — |
Countries
China
Contacts
Public ContactChen Weijun
Reproductive Hospital Affiliated to Jiangxi University of Traditional Chinese Medicine
Outcome results
None listed