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A prospective study of PPARa and IGFBP-2 associated with the development of gestational diabetes mellitus in infertile women with endometriosis

A prospective study of PPARa and IGFBP-2 associated with the development of gestational diabetes mellitus in infertile women with endometriosis

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2500095800
Enrollment
Unknown
Registered
2025-01-13
Start date
2025-01-16
Completion date
Unknown
Last updated
2025-01-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

endometriosis

Interventions

group 1:none
group 2:none

Sponsors

Shanghai First Maternity and Infant Hospital
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
20 Years to 35 Years

Inclusion criteria

Inclusion criteria: Age between 20-35 years, BMI between 19-24, basal FSH less than 10 IU/L, AMH more than 1.1 ng/ml , follicular number between 6-10. no history of hormone use in the three months prior to IVF treatment, no endometrial polyps, fibroids, adenomyosis, congenital uterine anomalies and tubal effusions, no major cardiac, hepatic, or renal disorders, and no history of diabetes mellitus. All women with endometriosis were diagnosed by laparoscopy and pathology, and all women with ovarian endometriosis had unilateral cysts of no more than 4 CM before IVF treatment. The control group patients did not have endometriosis, and they underwent IVF only due to tubal obstruction as suggested by tubal imaging results.

Exclusion criteria

Exclusion criteria: Women with infectious diseases, endocrine abnormalities, genetic abnormalities, or acquired or hereditary thrombosis.

Design outcomes

Primary

MeasureTime frame
Peroxisome Proliferator-Activated Receptor alpha;Insulin-like Growth Factor Binding Protein 2;

Countries

China

Contacts

Public ContactHe xiaoying

Shanghai First Maternity and Infant Hospital

xiaoyinghe1262024@126.com+86 185 1651 5820

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026