Oral potential malignant diseases (oral leukoplakia, erosive ulcerative lichen planus, erythema, chronic discoid lupus erythematosus, etc.)
Conditions
Interventions
Lesion group:Pulse ablation surgery
Sponsors
West China Hospital of Stomatology, Sichuan University
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1) 18 years old = age = 70 years old; 2) Patients diagnosed with oral potential malignant diseases (i.e. oral leukoplakia, erosive ulcerative lichen planus, etc.); 3) Bilateral lesions are distributed in relatively flat areas such as cheeks and tongue and are clearly visible; 4) Patients who voluntarily participate and sign the informed consent form and can cooperate to complete the entire trial process.
Exclusion criteria
Exclusion criteria: 1) Patients with severe epithelial dysplasia; 2) Carcinoma in situ or invasive cancer as shown by biopsy; 3) Active infection or open wound in the treatment area; 4) Untreated arrhythmia within two years; 5) Implanted cardiac pacemaker and/or other active implants; 6) Severe coagulation disorder or obvious bleeding tendency (platelet 1.5 times the upper limit of normal value); 7) Patients with contraindications to local anesthesia as assessed by the investigator; 8) Eating irritating food such as alcohol after surgery; 9) Patients with scar constitution; 10) Severe functional failure of major organs (heart, liver, kidney) (heart function grade =III; 1.ALT, AST >1.5 times the upper limit of normal value; 2.serum creatinine >1.5 times the upper limit of normal value); 11) Life expectancy less than 12 months; 12) Psychiatric patients who cannot cooperate with treatment; 13) Patients with other serious systemic diseases; 14) The patient is pregnant, breastfeeding or planning to become pregnant during the study; 15) The patient is currently participating in another clinical study involving the research product; 16) The researcher believes that there are other circumstances that make the patient unsuitable for participation in this clinical trial.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Clinical Effectiveness; | — |
Countries
China
Contacts
Public ContactLu Jiang
West China Hospital of Stomatology, Sichuan University
Outcome results
None listed