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Serum levels of NLRP3 in relation to 3-month functional outcome and early neurological deterioration after spontaneous intracerebral hemorrhage

Serum levels of NLRP3 in relation to 3-month functional outcome and early neurological deterioration after spontaneous intracerebral hemorrhage

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2500095785
Enrollment
Unknown
Registered
2025-01-13
Start date
2021-10-01
Completion date
Unknown
Last updated
2025-01-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Spontaneous cerebral hemorrhage

Interventions

Patients group:NA
Controls group:NA

Sponsors

Department of Neurosurgery, The First People's Hospital of Linping District
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: All patients were required to be hospitalized within 24 hours of symptom onset and be at least 18 years of age. None of the patients with cerebral hemorrhage received surgical treatment.

Exclusion criteria

Exclusion criteria: (1) previous neurological diseases (such as intracranial tumors, Parkinson's disease, Alzheimer's disease, aneurysmal subarachnoid hemorrhage, severe traumatic brain injury, and ischemic stroke); (2) Patients with secondary cerebral hemorrhage (such as ruptured intracranial aneurysm, intracranial tumor, arteriovenous malformation, moyamoya disease, ischemic stroke with hemorrhagic transformation). (3) Known malignancies or other specific diseases or conditions (such as pregnancy, heart failure, uremia, cirrhosis of the liver, infection, or surgery in the last month); (4) Incomplete patient data; (5) The blood sample is not available; (6) The patient or his authorized person refuses to participate in the study; (7) Loss of follow-up.

Design outcomes

Primary

MeasureTime frame
NLRP3;mRS scores;GCS scores;

Countries

China

Contacts

Public ContactJun Wang

The Frst People's Hospital of Linping District

wangjun57188@163.com+86 153 7200 2086

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026