Tonsil adenoid hypertrophy
Conditions
Interventions
No opioid group:Prior to induction: dexmedetomidine hydrochloride nasal spray was injected into both sides of the patients nostrils at a dose of 2ug/kg. Simple intravenous induction: dexamethasone 0.1
Or combined induction: sevoflurane inhalation induction by tidal volume method, intravenous access was opened after the child's consciousness disappeared, and intravenous anesthesia was given. After i
Control group:Simple intravenous induction: dexamethasone 0.15mg/kg (Max. 4mg), propofol 2.5-3mg/kg, rocuronium 0.6mg/kg, fentanyl 1-2ug/kg, mask manual ventilation for 3-5min to the requirements of m
Sponsors
Affiliated Hospital of Xuzhou Medical University
Eligibility
Sex/Gender
All
Age
3 Years to 12 Years
Inclusion criteria
Inclusion criteria: 1. American Society of Anesthesiologists (ASA) Class I-II pediatric patients; 2. Age 3-12 years old; 3. Tonsillar with (or with) adenoidectomy under general anesthesia; 4. Parents or guardians who can understand and sign the informed consent form.
Exclusion criteria
Exclusion criteria: 1. Known cardiopulmonary diseases (untreated congenital heart disease, primary or secondary pulmonary hypertension, tumors, structural lung diseases); 2. Those with neuromuscular diseases; 3. Maxillofacial deformity; 4. BMI> = 95th percentile of people of the same age and sex; 5. Severe upper respiratory tract infection, and the chief anesthesiologist recommends postponing surgery; 6. Those who are allergic to the study drug; 7. Refusal of parents or guardians to participate in this study; 8. Those who have poor compliance and request to quit; 9. Unable to continue to participate in the trial due to objective factors during the follow-up process; 10. Those who underwent tonsillectomy with (without adenoid) resection for the second time.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence of postoperative respiratory adverse events; | — |
Secondary
| Measure | Time frame |
|---|---|
| Recovery time;Duration of stay in anesthesia recovery room;Length of stay;Postoperative non-respiratory complications (including vomiting, bleeding, pharyngeal edema);Recovery delirium score (PAED for children recovering from anesthesia);Postoperative Pain Score (FLACC Scale);Number of PACU analgesic remedies and dosage of analgesic remedies;Heart rate;Pulse oxygen saturation; | — |
Countries
China
Contacts
Public ContactZhang Yueying
The Affiliated Hospital of Xuzhou Medical University
Outcome results
None listed