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The effect of continuous erector spinae plane block on cognitive function in elderly patients undergoing radical lung cancer surgery

The effect of continuous erector spinae plane block on cognitive function in elderly patients undergoing radical lung cancer surgery

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500095780
Enrollment
Unknown
Registered
2025-01-13
Start date
2025-02-10
Completion date
Unknown
Last updated
2025-01-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

lung cancer

Interventions

Group A experimental group:After anesthesia induction in the patient, ultrasound-guided ESPB was performed and catheterization was performed. At the end of the surgery, a pain p
Group B control group:Patient controlled intravenous analgesia

Sponsors

The first affiliated hostipal of nanchang university
Lead Sponsor

Eligibility

Sex/Gender
All
Age
60 Years to No maximum

Inclusion criteria

Inclusion criteria: 1.Patients undergoing selective single port thoracoscopic radical surgery for lung cancer; 2.Age 60 and above; 18.5g/? <=Body Mass Index (BMI)<28kg/?; 3.ASA II-III; 4.Expected intraoperative bleeding volume <=800ml; 5.Estimated surgical time <=3h; 6.Those who voluntarily participate and sign an informed consent form;

Exclusion criteria

Exclusion criteria: 1.Patients with severe cardiovascular, cerebrovascular, and pulmonary diseases, such as severe hypertension, have systolic blood pressure >= 180mmHg and diastolic blood pressure >=110mmHg; 2.Severe liver and kidney dysfunction patients; 3.Long term insomnia or taking sedatives; 4.Preoperative Mini Mental State Examination Scale (MMSE) for assessing cognitive impairment (criteria vary depending on education level: <=17 points for those with less than 1 year of education, <= 20 points for those with 1-5 years of education, <= 22 points for those with 6-9 years of education, and <= 23 points for those with more than 9 years of education); 5.Individuals with contraindications for puncture; 6.Morbidly obese individuals; 7.Individuals with a history of local anesthetic allergy;

Design outcomes

Primary

MeasureTime frame
The incidence of cognitive impairment;

Secondary

MeasureTime frame
Postoperative eye opening time;Oxygenation index;Adiponectin;Postoperative analgesia situation;Number of occurrences of nausea and vomiting;Time to remove tracheal tube;Postoperative removal time of closed thoracic drainage tube;heart rate;blood pressure;Average pressure;Intraoperative sufentanil dosage;Intraoperative remifentanil dosage;S-100 ß protein;Adverse reactions to local anesthetics;Adverse events of nerve block operation;Perioperative satisfaction score;

Countries

China

Contacts

Public Contactliujingdi

The first affiliated hostipal of nanchang university

601709616@qq.com+86 182 7091 0741

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026