lung cancer
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1.Patients undergoing selective single port thoracoscopic radical surgery for lung cancer; 2.Age 60 and above; 18.5g/? <=Body Mass Index (BMI)<28kg/?; 3.ASA II-III; 4.Expected intraoperative bleeding volume <=800ml; 5.Estimated surgical time <=3h; 6.Those who voluntarily participate and sign an informed consent form;
Exclusion criteria
Exclusion criteria: 1.Patients with severe cardiovascular, cerebrovascular, and pulmonary diseases, such as severe hypertension, have systolic blood pressure >= 180mmHg and diastolic blood pressure >=110mmHg; 2.Severe liver and kidney dysfunction patients; 3.Long term insomnia or taking sedatives; 4.Preoperative Mini Mental State Examination Scale (MMSE) for assessing cognitive impairment (criteria vary depending on education level: <=17 points for those with less than 1 year of education, <= 20 points for those with 1-5 years of education, <= 22 points for those with 6-9 years of education, and <= 23 points for those with more than 9 years of education); 5.Individuals with contraindications for puncture; 6.Morbidly obese individuals; 7.Individuals with a history of local anesthetic allergy;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The incidence of cognitive impairment; | — |
Secondary
| Measure | Time frame |
|---|---|
| Postoperative eye opening time;Oxygenation index;Adiponectin;Postoperative analgesia situation;Number of occurrences of nausea and vomiting;Time to remove tracheal tube;Postoperative removal time of closed thoracic drainage tube;heart rate;blood pressure;Average pressure;Intraoperative sufentanil dosage;Intraoperative remifentanil dosage;S-100 ß protein;Adverse reactions to local anesthetics;Adverse events of nerve block operation;Perioperative satisfaction score; | — |
Countries
China
Contacts
The first affiliated hostipal of nanchang university