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Effects of Combined Interval Blood Flow Restriction with High-Intensity Resistance Training on Lower Limb Muscle Strength and Power

Acute effects of Combined Interval Blood Flow Restriction with High-Intensity Resistance Training on Lower Limb Muscle Strength and Power

Status
Recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500095779
Enrollment
Unknown
Registered
2025-01-13
Start date
2024-09-03
Completion date
Unknown
Last updated
2025-01-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

CON-A:The traditional group performed blood flow restriction (BFR) squats at 80% of 1RM for 4 sets of 10 repetitions, with 180 seconds of rest between sets and no rest within sets
After the intervention was completed, the subjects in group A underwent intervention in groups B and C, with a 72 hour washout period set between each intervention group.
CS-B:CS-B performed blood flow restriction (BFR) exercises consisting of 80% 1RM loaded squats for 5 sets of 8 repetitions. Within each set, a 36-second intra-set rest was implemented every 4 repetiti
CS-C:CS-C performed blood flow restriction (BFR) exercises consisting of 80% 1RM loaded squats for 5 sets of 8 repetitions. Within each set, a 12-second intra-set rest was implemented every 2 repetiti

Sponsors

Wenzhou Medical University
Lead Sponsor

Eligibility

Sex/Gender
Male
Age
18 Years to 25 Years

Inclusion criteria

Inclusion criteria: 1.Male participants aged 18-25 years 2.At least two years of strength training experience 3.No major lower limb injuries in the past six months 4.No history of cardiovascular disease 5.Squat strength >= 1.5 times body weight

Exclusion criteria

Exclusion criteria: 1.Injury or Medical Conditions Presence of any acute or chronic injuries in the lower limbs that could interfere with participation in resistance training. Diagnosis of musculoskeletal disorders, including joint instability or chronic pain affecting lower limb function. 2.Neurological or Cardiovascular Disorders Any neurological conditions affecting motor control or muscle performance. History of cardiovascular or metabolic diseases that contraindicate high-intensity exercise or blood flow restriction protocols. 3.Training or Activity Limitations Current participation in a conflicting training program that may influence the outcomes of this study. Inability to perform proper squat techniques as required for the study protocol. 4.Use of Enhancing Substances Use of performance-enhancing drugs or supplements (e.g., anabolic steroids) in the past 12 months.

Design outcomes

Primary

MeasureTime frame
Vertical Jump Height;Relative Peak Power;Integrated Electromyography;Root Mean Square (RMS);Landing Hip Joint Angle;Landing Knee Joint Angle;Landing Ankle Joint Angle;Hip Range of Motion during Landing;Knee Range of Motion during Landing;Ankle Range of Motion during Landing;

Secondary

MeasureTime frame
Blood Lactate Concentration;Rating of Perceived Exertion(RPE);

Countries

China

Contacts

Public ContactZhanfei Zheng

Wenzhou Medical University

zhanfei1209@163.com+86 188 1093 7441

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026