liver transplantation
Conditions
Interventions
Remazolam group:Remazolam besylate was used for anesthesia induction and maintenance at doses of 0.2-0.4mg/kg and 1-3 mg/kg/h, respectively. During the operation, the dose was adjusted according to vi
Propofol group:Propofol was used for induction and maintenance of anesthesia, the doses were 1-2mg/kg and 4-12mg/kg/h, respectively, and the dose was modulated according to vital signs and BIS value o
Sponsors
Affiliated Hospital of Qingdao University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Age 18-60 years old 2. Liver transplant patients
Exclusion criteria
Exclusion criteria: 1. Living donor liver transplantation 2. Split liver transplantation 3. Second liver transplant 4. Allergy to remimazolam 5. CRRT before transplantation 6. Acute liver failure 7. Severe circulatory instability (hypertension, coronary heart disease, severe arrhythmia) 8. Multiple organ transplantation 9. Preoperative hepatic encephalopathy, disorder of consciousness
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Post reperfusion syndrome; | — |
Secondary
| Measure | Time frame |
|---|---|
| Postoperative invasive ventilator time;Postoperative ICU time;Anaesthesia induced hypotension;Postoperative delirium; | — |
Countries
China
Contacts
Public ContactLyu Lin
Affiliated Hospital of Qingdao University
Outcome results
None listed