Colorectal cancer
Conditions
Interventions
Individuals eligible for advanced colorectal neoplasia screening:Stool-based DNA methylation detection
home-based fecal hemoglobin/transferrin test
Colonoscopy
Sponsors
Shanghai Jiao Tong University
Eligibility
Sex/Gender
All
Age
45 Years to 74 Years
Inclusion criteria
Inclusion criteria: 1.Aged 45-74 years; 2.No history of colonic resection;
Exclusion criteria
Exclusion criteria: 1.History of colorectal cancer, and had received cancer-related therapy; 2.Has other non-gastrointestinal malignant neoplastic diseases; 3.Has serious disease of the heart, head, lung, liver, and kidney; 4.Has severe mental disorders, or language communication disorder; 5.Pregnant women;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Detection rate of advanced colorectal neoplasm (including colorectal cancer and advanced adenoma); | — |
Secondary
| Measure | Time frame |
|---|---|
| Compliance rate of colonoscopy;Detection rate of any colorectal neoplasm;Detection rate of colorectal neoplasm for home-based fecal hemoglobin/transferrin test;Efficacy of stool-based DNA methylation detection in the detection of colorectal neoplasia in high-risk subgroup; | — |
Countries
China
Contacts
Public ContactHongchen Gu
Shanghai Jiao Tong University
Outcome results
None listed