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To observe the intestinal function in both healthy individuals and patients undergoing cardiopulmonary bypass (CPB) by measuring the levels of biomolecules related to intestinal function in the blood

To observe the intestinal function in both healthy individuals and patients undergoing cardiopulmonary bypass (CPB) by measuring the levels of biomolecules related to intestinal function in the blood

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2500095759
Enrollment
Unknown
Registered
2025-01-13
Start date
2025-01-13
Completion date
Unknown
Last updated
2025-01-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Intestinal function impairment after cardiopulmonary bypass

Interventions

Control group:None
Observation group:None

Sponsors

The Affiliated Hospital of Southwest Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1. Age: > = 18 years old 2. Healthy physical examiners or patients undergoing cardiac surgery under cardiopulmonary bypass (time > 2h), ASA class I-III. 3. Signed informed consent 4. Participated in other clinical trials in the past 3 months

Exclusion criteria

Exclusion criteria: 1. History of copper metabolism-related diseases 2. History of intestinal disease 3. Pregnant and lactating women

Design outcomes

Primary

MeasureTime frame
Diamine oxidase(DAO);D-lactate;Intestinal fatty acid binding protein(iFABP);—

Secondary

MeasureTime frame
Cuprous ion(Cu+);Ferrous iron ion(Fe2+);Tumor necrosis factor-alpha(TNF-a);Interleukin-6(IL-6);Interleukin-10(IL-10);Reduced glutathione(GSH);—

Countries

China

Contacts

Public ContactZhou Jun

the Affiliated Hospital of Southwest Medical University

47147381@qq.com+86 187 1581 6677

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026