critically ill
Conditions
Interventions
Propofol disodium phosphate group:The initial dose of propofol disodium is 3.5mg/kg/h, and the titration range is 0-10mg/kg/h
Propofol group:The initial dose of propofol transport is 2.0mg/kg/h, and the titration range is 0-4mg/kg/h
Sponsors
Tianjin Nankai Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1) Severely ill patients who need to be transferred to the ICU for close monitoring after surgery based on preoperative or intraoperative evaluation. 2) The patient is aged between 18 and 75 years old, with no gender restrictions.
Exclusion criteria
Exclusion criteria: 1) Patients who require deep sedation (RASS40kg/m2); 8) Have a history of allergy to anesthesia or analgesic drugs related to this experiment; 9) Pregnant or lactating female patients; 10) There are other medication or clinical contraindications that are expected to affect the trial; 11) Individuals who have been selected or participated in other clinical trials within the past 6 months; 12) According to the researchers' judgment, patients are not suitable for inclusion in other situations, such as extremely unstable vital signs, being in a critical state, and potential disputes.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The success rate of sedation during postoperative transportation; | — |
Secondary
| Measure | Time frame |
|---|---|
| The number and total amount of additional sedatives added;Changes in blood oxygen saturation, heart rate, and blood pressure during postoperative transportation;The incidence and types of serious adverse events and adverse events;Usage of vasoactive drugs: types, doses;Mortality rate during ICU hospitalization; | — |
Countries
China
Contacts
Public ContactYu Jianbo
Tianjin Nankai Hospital
Outcome results
None listed