Insomnia disorder
Conditions
Interventions
sham a-cTBS group:sham a-cTBS treatment
Sponsors
Affiliated Kangning Hospital of Ningbo University
Eligibility
Sex/Gender
All
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: (1) Age 18~60 years old; (2) diagnostic criteria for insomnia disorders in the International Classification of Diseases and Related Health Problems, Revision 11 (ICD-11); (3) The total score of PSQI is >5; (4) right-handed; (5) The patient's physical examination, medical history, vital signs, hematuria and stool routine, liver and kidney function, electrolytes, electrocardiogram, electroencephalogram and other indicators were normal; (6) After fully understanding the safety of transcranial magnetic stimulation (TMS), willing to actively cooperate with the treatment, and sign the informed consent by the person and his family.
Exclusion criteria
Exclusion criteria: (1) Patients with severe physical diseases, infectious diseases and immune system diseases; (2) Patients with severe neurological diseases, mental retardation or cerebral organic diseases; (3) The patient has metal or electronic devices built into the body, such as intracranial metal foreign bodies, cochlear implants, pacemakers, stents and other metal foreign bodies; (4) Have a risk of seizures, have previous craniocerebral disease, head trauma, alcoholism, electroencephalogram abnormalities, MRI evidence of brain structural abnormalities, or have a family history of epilepsy; (5) ECT treatment within 2 months prior to enrollment; (6) Those who have psychotic symptoms and need to be combined with antipsychotic drugs; (7) Those who are pregnant, breastfeeding, or planning to become pregnant during the trial.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The Hamilton Depression Scale (HAMD);The Hamilton Anxiety Scale (HAMA);The Pittsburgh Sleep Quality Index (PSQI);The Clinical General Impressions Scale (CGI) ;Sleep diary; | — |
Secondary
| Measure | Time frame |
|---|---|
| Electromyographic changes;EEG changes;Near infrared functional imaging;3.0T Nuclear Magnetic (MRI); | — |
Countries
China
Contacts
Public ContactQi Zhou
Affiliated Kangning Hospital of Ningbo University
Outcome results
None listed