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The study on the effect of sodium diclofenac suppositories for postoperative analgesia after repeat cesarean section.

The study on the effect of sodium diclofenac suppositories for postoperative analgesia after repeat cesarean section.

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500095734
Enrollment
Unknown
Registered
2025-01-13
Start date
2025-01-15
Completion date
Unknown
Last updated
2025-01-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

scarred uterus

Interventions

Diclofenac Sodium Suppository Treatment Group:After surgery, 2mg of epidural morphine + 100mcg of sufentanil (Patient-Controlled Intravenous Analgesia, PCIA) + 50mg of diclofenac sodium suppository we
Glycerin Suppository Control Group:After surgery, 2mg of epidural morphine + 100mcg of sufentanil (Patient-Controlled Intravenous Analgesia, PCIA) + 50mg of glycerin suppository were administered rect

Sponsors

Hunan Provincial Maternal and Child Health Hospital
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to 45 Years

Inclusion criteria

Inclusion criteria: (1) Full-term pregnancy; (2) Elective repeat cesarean section; (3) Age between 18 and 45 years old; (4) ASA Class I-II; (5) Body Mass Index (BMI) greater than 20kg/m^2 and less than 35kg/m^2; (6) Mothers who have signed the informed consent form and are able to cooperate with the completion of the study.

Exclusion criteria

Exclusion criteria: (1) Contraindications for spinal anesthesia; (2) Known allergy to diclofenac sodium; (3) Allergy to nonsteroidal anti-inflammatory drugs (NSAIDs) or severe allergic constitution; (4) Intolerance or history of adverse reactions to opioids; (5) Chronic pain or long-term use of sedative analgesics; (6) History of severe cardiovascular diseases such as hypertension and heart disease; (7) History of gastrointestinal ulcers, bleeding, or other related diseases.

Design outcomes

Primary

MeasureTime frame
Visual Analogue Scale pain scores;

Secondary

MeasureTime frame
Satisfaction score;The time of the first breastfeeding;The time of the first time getting out of bed;The time of first anal passage of gas;Postoperative blood loss;Number of adverse reaction occurrences;

Countries

China

Contacts

Public ContactZhang Jie

Hunan Provincial Maternal and Child Health Hospital

zhangj0909@yeah.net+86 135 7485 9376

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026