Sellar region lesions
Conditions
Interventions
Growth hormone treatment group (retrospective section):None
Non growth hormone treatment group (retrospective section):None
Observation group (prospective section):None
Sponsors
Shanghai Children's Hospital
Eligibility
Sex/Gender
All
Age
1 Years to 18 Years
Inclusion criteria
Inclusion criteria: a. Definitive diagnosis of sellar region lesions (as agreed upon by multidisciplinary consensus including neurosurgery, radiology, oncology, and endocrinology) b. Imaging or pathological evidence is available c. Patients have undergone or are undergoing surgical, radiotherapeutic, and/or chemotherapeutic interventions d. Comprehensive endocrine evaluations are documented e. Baseline metabolic assessment data are available f. Robust follow-up data are available g. Patients have received or are currently receiving endocrine hormone therapy h. Detailed and standardized electronic medical records or convertible forms are maintained;
Exclusion criteria
Exclusion criteria: a. The patient's neuroendocrine system exhibited severe impairment, and the caregiver was unable to provide adequate support. b. The lesions were widespread, with the sellar region not being the primary affected area. c. Metastatic tumors were present in the sellar region. d. Any other conditions that the investigator deemed unsuitable for trial inclusion.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| HtSDS;Tumor-free survival; | — |
Secondary
| Measure | Time frame |
|---|---|
| Pituitary hormone levels (including thyroid function, adrenal function, vasopressin, sex hormones, etc.);Lipid metabolism levels;Assessment of Sexual development;Quality of Life; | — |
Countries
China
Contacts
Public ContactSheng Guo
Shanghai Children's Hospital
Outcome results
None listed