subclinical atherosclerotic diseases
Conditions
Interventions
Observation group:None
Sponsors
Xuanwu Hospital Capital Medical University
Eligibility
Sex/Gender
All
Age
16 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1.(1) Combined with at least one cardiovascular disease risk factor, such as hypertension, family history of cardiovascular disease, diabetes, hyperlipidemia, smoking, obesity, etc. 2.(2) Based on routine hospital tests, cardiovascular ultrasound, coronary CTA and other auxiliary examinations, Vascular and endothelial function tests such as brachial-ankle pulse wave velocity (baPWV) and flow-mediated dilation (FMD), Patients diagnosed without definite atherosclerotic disease. 3.(3) Understand the research protocol, voluntarily participate in the study, and sign the informed consent.
Exclusion criteria
Exclusion criteria: 1.(1) Patients with a history of severe atherosclerotic cardiovascular and cerebrovascular events, including a history of old myocardial infarction, acute coronary syndrome, and ischemic/hemorrhagic stroke, as well as patients with suspicious symptoms of transient ischemic attack in the past, who were found to have cardiac embolism or major artery disease. 2.(2) symptomatic peripheral vascular disease, including prior revascularization or amputation; 3.(3) Improve the diagnosis of patients with atherosclerotic diseases after admission tests and examinations; 4.(4) Patients allergic to iodine contrast media; 5.(5) have combined severe liver insufficiency and/or severe renal insufficiency (estimated glomerular filtration rate [eGFR] < 30 ml/min); 6.(6) combined with other infectious diseases, including respiratory system infection, urinary system infection, etc.; 7.(7) Combined with rheumatological and other metabolic diseases, including systemic vasculitis, lupus erythematosus, thyroid dysfunction, etc.; 8.(8) Multiple organ failure and unstable vital signs have been diagnosed with advanced malignant tumors; 9.(9) Pregnant or lactating patients; 10.(10) Suffering from mental illness and unable to cooperate with researchers; 11.(11) Other patients not suitable to participate in this study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence of cardiovascular events (coronary heart disease, myocardial infarction), stroke (hemorrhagic, ischemic), revascularization of any artery, and death (cardiogenic, non-cardiogenic); | — |
Countries
China
Contacts
Public ContactLi jing
Xuanwu Hospital Capital Medical University
Outcome results
None listed