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Discontinuation of aspirin in pregnancy hypertensive high risk women according to sFLT-1/PIGF ratio during 26-28 gestational week

Discontinuation of aspirin in pregnancy hypertensive high risk women according to sFLT-1/PIGF ratio during 26-28 gestational week

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500095679
Enrollment
Unknown
Registered
2025-01-10
Start date
2025-06-01
Completion date
Unknown
Last updated
2025-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

preeclampsia

Interventions

Intervention group:Stop taking aspirin
Control group:Take aspirin until 36 weeks of pregnancy

Sponsors

shanghai first maternity and infant hospital
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to 45 Years

Inclusion criteria

Inclusion criteria: 1. Pregnant women aged 18 or older, singleton pregnancies, with gestational age between 11+0 and 13+6 weeks at the time of visit, with normal NT results; 2. Fully informed and have signed an informed consent form; 3. According to the ACOG Guidelines for the Diagnosis and Management of Preeclampsia in Pregnancy (2018), have at least one risk factor for preeclampsia or two moderate risk factors; 4. According to the UK Pregnancy Foundation's early pregnancy formula, the risk of developing preeclampsia during pregnancy is greater than 1/100; 5. Pregnant women who plan to have prenatal care and delivery at our hospital.

Exclusion criteria

Exclusion criteria: 1. Multiple pregnancies; 2. Starting to take aspirin after 17 weeks of pregnancy; 3. Aspirin adherence <80%; 4. Allergy or intolerance to aspirin; 5. Fetal malformations.

Design outcomes

Primary

MeasureTime frame
preterm preeclampsia;early onset preeclampsia;

Countries

china

Contacts

Public Contacthuaxiaolin

shanghai first maternity and infant hospital

huaxiaolin_sh@163.com+86 189 3050 2621

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026