Emergence Agitation , EA
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1.Age >=18 years; 2.Scheduled for general anesthesia undergoing laparoscopic radical surgery for gastric cancer or colorectal cancer with an expected duration of 2 hours or longer; 3.ASA classification of 2 to 3;
Exclusion criteria
Exclusion criteria: 1.Allergy to study drugs such as remimazolam or sevoflurane; 2.Pre-existing cognitive impairment; 3.Severe hearing impairment; 4.History of mental illness or long-term use of sedative or antidepressant medications; 5.Presence of severe organic diseases, such as liver or kidney dysfunction; 6.BMI >35 kg/m²; 7.Deemed unsuitable for participation in the study by the researcher;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence of emergence agitation; | — |
Secondary
| Measure | Time frame |
|---|---|
| The incidence of severe agitation;The time to bispectral index (BIS) value recovery to 80;Time to extubation;Sufentanil and propofol dosage used in the PACU;Time to full emergence from anesthesia;Length of stay in post-anesthesia care unit (PACU);Incidence of postoperative delirium during hospitalization;Incidence of nausea and vomiting during the first 24 h after surgery;Quality of recovery in the first postoperative day;length of postoperative hospital stay;Mean arterial pressure and heart rate;The incidence of intraoperative hypotension;The incidence of bradycardia;Incidence of drowsiness after extubation;Incidence of resedation;Incidence of hypoxemia after extubation;Incidence of intraoperative awareness; | — |
Countries
China
Contacts
People's Hospital of Jianyang City