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An exploratory study on organochip drug sensitivity detection to predict the efficacy of target drugs for rare tumors such as gastrointestinal stromal tumor

An exploratory study on organochip drug sensitivity detection to predict the efficacy of target drugs for rare tumors such as gastrointestinal stromal tumor

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2500095659
Enrollment
Unknown
Registered
2025-01-10
Start date
2025-01-10
Completion date
Unknown
Last updated
2025-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Gastrointestinal stromal tumor and other rare malignant tumors

Interventions

Observation group:None

Sponsors

Arion Cancer Center
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1.Patients with rare tumors with definite clinical or pathological diagnosis, such as gastrointestinal stromal tumors; The clinical criteria are as follows: a. Patients with rare tumors who can be clinically evaluated for R0 surgery by neoadjuvant therapy/conversion therapy; b. Patients with advanced rare tumors; 2.Age >=18 years; 3.ECOG score <=2 points or ECOG score 3-4 points due to tumor progression; 4.Survival is expected to exceed 3 months; 5.Samples such as surgical, biopsy tissue or malignant effusion can be obtained; 6.Patients volunteered to join the study and signed informed consent.

Exclusion criteria

Exclusion criteria: 1.With active tuberculosis (TB); 2.Previous tissue/organ transplants; 3.Pregnant or lactating women; 4.Exclusion criteria are not listed for patients who are considered unsuitable for participation in this clinical study.

Design outcomes

Primary

MeasureTime frame
The accuracy of drug susceptibility test results in predicting the main clinical efficacy evaluation index (RECIST1.1 criteria).;Objective response and overall objective response rate;

Secondary

MeasureTime frame
Level of change in tumor markers;

Countries

China

Contacts

Public ContactZhiqiang Ma

Arion Cancer Center

zhiqiang.ma@arion.care+86 10 81215503

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026