Network analysis of dentofacial morphology and early orthodontic treatment efficacy for children with skeletal class II and class III malocclusion based on multimodal fusion models

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2500095643

Enrollment

Unknown

Registered

2025-01-09

Start date

2025-01-10

Completion date

Unknown

Last updated

2025-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Malocclusion

Interventions

A:Using Activator for the treatment of skeletal Class II malocclusion

B:Using Twin-block for the treatment of skeletal Class II malocclusion

C:Using maxillary protraction appliance for the treatment of skeletal Class III malocclusion

D:Using Frainkel-III for the treatment of skeletal Class III malocclusion

Eligibility

Sex/Gender

All

Age

7 Years to 15 Years

Inclusion criteria

Inclusion criteria: 1) From October 2024 to December 2026, patients with skeletal Class II malocclusion who underwent early orthodontic treatment using Twin-block or Activator, as well as patients with skeletal Class III malocclusion who underwent early orthodontic treatment using maxillary protraction appliances or Frankel-III, in the orthodontic department of Peking University Hospital of Stomatology. 2) Patients with complete and high-quality digital dental models, digital three-dimensional facial scans, and CBCT images before and after treatment. 3) The cervical vertebral maturation stage is <=CS5.

Exclusion criteria

Exclusion criteria: 1) Patients with diseases related to the nasopalatine region. 2) Patients with congenital craniofacial syndromes or other rare growth and developmental abnormalities.

Design outcomes

Primary

Measure	Time frame
The three-dimensional network analysis model for characteristic dentofacial features before treatment in adolescent patients with skeletal Class II and Class III malocclusion;Network analysis model for three-dimensional changes in characteristic dentofacial features before and after early orthodontic treatment in adolescent patients with skeletal Class II and Class III malocclusion;	—

Secondary

Measure	Time frame
Accuracy of automatic localization for three-dimensional craniofacial and dental landmarks;Accuracy of Multimodal Model Fusion;	—

Countries

China

Contacts

Public ContactGuangying Song

Peking University Hospital of Stomatology

songguangying@sina.com+86 133 1152 8361

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026