Body movement response during ocular regional blockade
Conditions
Interventions
Propofol-alfentanil-lidocaine mixture group:MAC using a Propofol-Alfentanil-Lidocaine mixture
Sponsors
The Zhongshan Ophthalmic Center, Sun Yat-sen University
Eligibility
Sex/Gender
All
Age
18 Years to 85 Years
Inclusion criteria
Inclusion criteria: 1.Aged 18 to 85 years old; 2.Selective ophthalmic day surgery; 3.Allocated to receive peribulbar/retrobulbar block under monitored anesthesia care(MAC); 4.The American Society of Anesthesiologists (ASA) physical status ?-?; 5.Agreed to sign the informed consent form for the trial;
Exclusion criteria
Exclusion criteria: 1.Uncontrolled malignant hypertension (>=180/110 mmHg); 2.Severe cardiac arrhythmias including sick sinus syndrome, second-degree and third-degree atrioventricular block, double-bundle branch block, and severe bradycardia (heart rate = 3); 8.Morbid obesity (BMI >=30 kg/m²); 9.History of allergy to study drugs; 10.Cognitive impairment precluding the ability to respond to study questionnaires; 11.Hearing impairment;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Ramsay score and motor response during ocular block after administration of propofol-alfentanil-lidocaine mixture for 1 minute;ED50; | — |
Secondary
| Measure | Time frame |
|---|---|
| Perioperative adverse events;Intraoperative sedation and analgesia index;Body movement responses;Numeric rating scale pain score;Time from PACU admission to achieving a modified Aldrete score >=9;Iowa Satisfaction with Anesthesia Scale (ISAS);Vital signs; | — |
Countries
China
Contacts
Public ContactWang Yongyi
The Zhongshan Ophthalmic Center, Sun Yat-sen University
Outcome results
None listed