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Investigation of Changes in Brain Function after Implantation of Different Types of Intraocular Lenses Based on fNIRS Research

Investigation of Changes in Brain Function after Implantation of Different Types of Intraocular Lenses Based on fNIRS Research

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2500095595
Enrollment
Unknown
Registered
2025-01-09
Start date
2025-03-01
Completion date
Unknown
Last updated
2025-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cataract

Interventions

Monofocal Intraocular Lens Group:NO
Multifocal Intraocular Lens Group:NO
Continuous-range-of-vision Intraocular Lens Group:NO

Sponsors

Affiliated Eye Hospital of Shandong University of Traditional Chinese Medicine
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: (1) Patients clinically diagnosed with age-related cataract or secondary cataract, who need to undergo phacoemulsification and intraocular lens implantation; (2) Age over 18 years old, gender; (3) Lens nucleus hardness <= grade IV; (4) Preoperative corneal astigmatism less than 1.5D; (5) Have sufficient cognitive ability to understand the research content and be able to cooperate with all tests during the research process; (6) Good surgical indications, and informed consent from the patient and their family.

Exclusion criteria

Exclusion criteria: (1) Patients with concurrent diseases such as glaucoma, retinopathy, corneal disease, and old ocular inflammation; (2) Those who have undergone ophthalmic surgery; (3) Patients with corneal endothelial cell count lower than 2000 cells/mm^2; (4) Patients with contraindications for cataract surgery such as intraocular inflammation; (5) Patients with severe systemic diseases that prevent them from cooperating to complete the study; (6) Patients using drugs that may affect vision or brain function and cannot discontinue them during the study; (7) Pregnant or lactating women; (8) Patients who fail to have regular postoperative check-ups; (9) Patients with unrealistic expectations regarding postoperative visual quality.

Design outcomes

Primary

MeasureTime frame
Oxygenated hemoglobin content;Defocus curve;Objective Visual Quality Assessment Indicator – Strelby;Objective visual quality evaluation index - area ratio;diopter;eyesight;intraocular pressure;Cataract Function Questionnaire;reading ability;

Countries

China

Contacts

Public ContactLiu Dongmei

Affiliated Eye Hospital of Shandong University of Traditional Chinese Medicine

13854191223@163.com+86 138 5419 1223

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026