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Effect of oxycodone on general anesthesia in patients undergoing cerebral endovascular procedures: A randomized controlled, single-center clinical trial

Effect of oxycodone on general anesthesia in patients undergoing cerebral endovascular procedures: A randomized controlled, single-center clinical trial

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500095589
Enrollment
Unknown
Registered
2025-01-09
Start date
2025-01-10
Completion date
Unknown
Last updated
2025-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cerebrovascular disease

Interventions

Sufentanil group:Sufentanil as an opioid would be used to the induction of general anesthesia
oxycodone group:Oxycodone as an opioid would be used to the induction of general anesthesia

Sponsors

Henan Provincial People's Hospita,medical
Lead Sponsor

Eligibility

Sex/Gender
All
Age
20 Years to No maximum

Inclusion criteria

Inclusion criteria: 1.Selective need laryngeal mask airway ventilation under general anesthesia to accept cerebrovascular interventional therapy; 2.ASA Classification: I-III; 3.Age =20 years old;

Exclusion criteria

Exclusion criteria: 1.BMI 2; 4.NIHSS Classification > 6; 5.Known allergies to analgesics or sedatives; 6.Acute severe stroke occurred within two weeks; 7.Communication difficulties; 8.Disturbance of consciousness; 9.alcoholism; 10.Long-term history of use of sedatives or opioid analgesics; 11.Epilepsy; 12.Pregnancy; 13.Mental illness; 14.Severe abnormality of coagulation function; 15.Severe impairment of liver and kidney function; 16.Circulation collapse, respiratory failure; 17.Severe sinus bradycardia (< 50 beats/min) or second degree atrioventricular block or above were present before operation;

Design outcomes

Primary

MeasureTime frame
RASS score;

Secondary

MeasureTime frame
NRS score;Recover: wake-up time, eye-opening time, time to remove the laryngeal mask, directional force recovery time;;the incidence of CRBD;Incidence of postoperative adverse events;Incidence of delirium;NIHSS score;mRS score;5-HT;

Countries

China

Contacts

Public ContactEnqiang Chang

Henan Provincial People's Hospita,medical

changenqiang@henu.edu.cn+86 15890125781

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026