Oral cancer
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1.Aged 18 to 75 years, male or female; 2.Subjects with histopathologically confirmed oral cancer; 3.Subjects with definite measurable lesions; 4.Subjects or the guardian agree to participate in the clinical trial and sign the Informed Consent Form before enrollment.
Exclusion criteria
Exclusion criteria: 1. Subjects that have received adjuvant therapy since diagnosis(eg:chemotherapy, radiotherapy or immunotherapy); 2.Subjects with any other malignant diseases in the last 5 years (except cured skin cancer and cervical carcinoma in situ); 3. Have received or is undergoing any other clinical drug trials or other gene therapy, cell therapy; 4. Pregnant and lactating women; 5. Any uncontrollable active infection; 6. HIV positive; 7. Treponema pallidum positive; 8. HCV positive; 9. Subjects who are using immunosuppressants or systemic steroids (except inhalation therapy); 10. Subjects with primary immunodeficiency or bone marrow deficiency; 11. Others: Subjects are not suitable for the study judged by investigators.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| cell number of TIL in tissue;Immunophenotype of TIL;Tumor cell killing effect of TIL; | — |
Countries
China
Contacts
Xiangya Stomatological Hospital, Central South University