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Study on the efficacy and safety of romiplostim N01 in treating thrombocytopenia before transcatheter hepatic artery chemoembolization for liver cancer

Study on the efficacy and safety of romiplostim N01 in treating thrombocytopenia before transcatheter hepatic artery chemoembolization for liver cancer

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500095567
Enrollment
Unknown
Registered
2025-01-08
Start date
2025-01-15
Completion date
Unknown
Last updated
2025-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Thrombocytopenia associated with liver cancer

Interventions

Hepatocellular carcinoma with thrombocytopenia:Roprostim raises platelets

Sponsors

Zhejiang Cancer Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 75 Years

Inclusion criteria

Inclusion criteria: 1.Age 18-75 years old, gender unlimited; 2.Hepatocellular carcinoma confirmed by histopathology or cytology or clinical diagnosis; 3.Transcatheter hepatic arterial chemoembolization was planned within 2 weeks after enrollmen; 4.If the platelet count is < 50×10^9/L, the washout period is 2 weeks if other platelet enhancing drugs have been used; 5.Liver function Child-Pugh grade A or B; 6.Understand the study procedure and sign the informed consent in person;

Exclusion criteria

Exclusion criteria: 1.Patients after liver transplantation or splenectomy; 2.Patients with hepatic encephalopathy; 3.Patients with uncontrolled abdominal fluid accumulation; 4.Portal vein thrombosismbosis; 5.Comorbid hematologic diseases; 6.Poor response to TPO receptor agonists is known; 7.Other conditions deemed unsuitable for inclusion by the researchers;

Design outcomes

Primary

MeasureTime frame
Platelet count;

Countries

China

Contacts

Public ContactZeng Hui

Zhejiang Cancer Hospital

zenghui@zjcc.org.cn+86 139 8989 8089

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026