Benign uterine fibroids / high-grade intraepithelial neoplasia / abnormal endometrial bleeding
Conditions
Interventions
Group A:Pump infusion of esketamine 2.5ug/kg/min
Group B:Pump infusion of esketamine 5ug/kg/min
Group C:Pump equal volume physiological saline
Sponsors
Dalian Medical University Affiliated Second Hospital
Eligibility
Sex/Gender
Female
Age
20 Years to 55 Years
Inclusion criteria
Inclusion criteria: 1. Meets the treatment criteria for laparoscopic total hysterectomy; 2. Age 20-55 years old, ASA grade I-III, BMI 18-28 kg/m^2; 3. Complete clinical data and voluntary participation in the study.
Exclusion criteria
Exclusion criteria: 1. Malignant tumor patients; 2. Patients with severe functional disorders of important organs such as the heart, brain, and kidneys; 3. Patients with preoperative mental dysfunction; 4. Individuals with a history of psychotropic drugs, opioid drugs, and alcohol dependence; 5. Individuals who are allergic to esketamine and have contraindications for the use of esketamine.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Postoperative recovey quality; | — |
Secondary
| Measure | Time frame |
|---|---|
| Visal pain simulation score;Postoperative adverse reactions; | — |
Countries
China
Contacts
Public ContactGao Jinxia
Dalian Medical University Affiliated Second Hospital
Outcome results
None listed