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A novel diagnostic model based on quantitative EBV-DNA and inflammation markers for the efficacy study of infectious mononucleosis in children

A novel diagnostic model based on quantitative EBV-DNA and inflammation markers for the efficacy study of infectious mononucleosis in children

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2500095546
Enrollment
Unknown
Registered
2025-01-08
Start date
2025-01-08
Completion date
Unknown
Last updated
2025-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Infectious mononucleosis

Interventions

Gold Standard:There were three joint diagnoses: atypic lymphocyte ratio, EBV antibody and nucleic acid detection
Index test:LASSO analysis was used to screen for clinical features and laboratory markers relevant to the diagnosis of IM and to establish a model and model calculation formulas, which calculate risk

Sponsors

Sun Yat-sen Memorial Hospital, Sun Yat-sen University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
No minimum to 18 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria for the leaflet group: the patient visited our hospital for the first time and did not receive any treatment before blood drawing; The patient has complete clinical data and meets the diagnostic criteria for infectious mononucleosis; Age less than 18 years. Control group inclusion criteria: Patient does not have diagnostic criteria for infectious mononucleosis and other diseases caused by EBV; Age less than 18 years.

Exclusion criteria

Exclusion criteria: Leaflet group exclusion criteria: patients with congenital malformations, other diseases not caused by EBV before presentation; Received other treatments prior to presentation; Age greater than 18 years. Control group exclusion criteria: Patient with disease caused by EBV; Received other treatments prior to presentation; Age greater than 18 years.

Design outcomes

Primary

MeasureTime frame
EBV-DNA;

Countries

China

Contacts

Public ContactGu Wenshen

Sun Yat-sen Memorial Hospital, Sun Yat-sen University

guwenshen0213@163.com+86 20 81332072

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026