large periapical lesions
Conditions
Interventions
Small intestinal submucosa membrane:guided tissue regeneration using small intestinal submucosa membrane in endodontic microsurgery
Concentrated growth factor:guided tissue regeneration using concentrated growth factor in endodontic microsurgery
Sponsors
Hospital of Stomatology, SunYat-sen University
Eligibility
Sex/Gender
All
Age
12 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1. The patient's age is 12-70 years old; 2. X-ray and CBCT show that the maximum diameter of periapical radiolucency is at least 10mm; 3. Deny systemic diseases; 4. The patient is a resident population of Guangdong with good compliance and informed consent.
Exclusion criteria
Exclusion criteria: 1.Teeth with severe periodontitis, root fracture, root bifurcation or perforation of the lateral wall of the root canal; 2.Teeth with root absorption exceeding one-third of the root; 3.Patients with systemic diseases who cannot tolerate surgery; 4.Patient who does not comply or the researcher believes that the patient cannot complete the entire clinical trial; 5.The patient has a history of smoking; 6.The patient is pregnant or breastfeeding;
Design outcomes
Secondary
| Measure | Time frame |
|---|---|
| the complete healing rate; | — |
Primary
| Measure | Time frame |
|---|---|
| percentage reduction of size of periapical lesion; | — |
Countries
China
Contacts
Public ContactYang Ruiqi
Hospital of Stomatology, SunYat-sen University
Outcome results
None listed