cervical cancer
Conditions
Interventions
Gold Standard:Colposcopic cervical biopsy results
Index test:p16/ki-67 double stain test, HR-HPV DNA test, LBC test
Sponsors
Peking Union Medical College Hospital
Eligibility
Sex/Gender
Female
Age
25 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1) Women aged 25-65 years old who attend outpatient clinics and have a sexual life history; 2) Women who meet the cervical cancer opportunistic screening population (including clinicians who recommend such screening and patients who themselves request cervical cancer screening)
Exclusion criteria
Exclusion criteria: 1) Women with no history of sexual life; 2) Pregnant or lactating women; 3) acute inflammation of reproductive tract; 4) Women who had cervical exfoliated cells collected within 2 months prior to this study; 5) Women to be referred for colposcopy or women with negative colposcopy results within one year; 6) Women with immune deficiencies; 7) Women with a previous diagnosis of CIN or cervical cancer; 8) Women with a history of other gynecological malignancies; 9) Women with a history of hysterectomy; 10) Women with a history of pelvic radiation therapy; 11) Women who have previously undergone surgical treatment for cervical lesions (LEEP knife, cold knife coning, etc.) 12) Women who have had vaginal medication or physical therapy within the past 3 months; 13) Women with mental disorders.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| sensitivity;specificity;Positive predictive value;Negative predictive value; | — |
Countries
China
Contacts
Public ContactXiang Yang
Peking Union Medical College Hospital
Outcome results
None listed