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Short-term Efficacy and Safety Evaluation of Natural Orifice Specimen Extraction Surgery for Gastrointestinal Tumors

The cohort study on the short-term efficacy and safety assessment of NOSES surgery for gastrointestinal tumors

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2500095508
Enrollment
Unknown
Registered
2025-01-08
Start date
2025-01-15
Completion date
Unknown
Last updated
2025-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

gastrointestinal tumors

Interventions

NOSES group:NA
Traditional laparoscopic surgery group:NA

Sponsors

The Third Affiliated Hospital Sun Yat-sen University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1. Histopathological examination confirms the diagnosis of adenocarcinoma or precancerous lesions. 2. Preoperative imaging assessment reveals that the tumor has not penetrated the serosal layer (T=3) and there is no distant metastasis, no peritoneal seeding, and no invasion of adjacent organs. 3. Body mass index (BMI) < 30 kg/m². 4. Enhanced Recovery After Surgery (ERAS) protocol is implemented during the perioperative period.

Exclusion criteria

Exclusion criteria: 1. The tumor can be resected endoscopically or locally via the anus. 2. Patients who are unsuitable for laparoscopic surgery. 3. Patients who require emergency surgery due to severe perforation, bleeding, obstruction, etc., prior to the operation. 4. Patients who undergo combined surgery at other surgical sites or who are converted to open surgery during the procedure. 5. Synchronous multiple primary cancers. 6. Recurrent cases.

Design outcomes

Primary

MeasureTime frame
Short-term efficacy;safety;

Secondary

MeasureTime frame
Postoperative recovery status;Surgical-related indicators;

Countries

China

Contacts

Public ContactWei Bo

The Third Affiliated Hospital Sun Yat-sen University

weibo3@mail.sysu.edu.cn+86 13527794069

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026