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Efficacy and Safety of Sedation with Remimazolam in Electrical Cardioversion of Atrial Fibrillation: A Prospective Randomized Controlled Trial

Efficacy and Safety of Sedation with Remimazolam in Electrical Cardioversion of Atrial Fibrillation: A Prospective Randomized Controlled Trial

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500095498
Enrollment
Unknown
Registered
2025-01-08
Start date
2025-01-15
Completion date
Unknown
Last updated
2025-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Atrial Fibrillatio

Interventions

propofol group:propofol
remimazolam and flumazenil group:remimazolam and flumazenil

Sponsors

Department of Cardiovasology Changhai Hospital Naval Medical University Shanghai
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 90 Years

Inclusion criteria

Inclusion criteria: 1.planned to receive electrical cardioversion 2. age =18 years 3. subjects are willing to sign an informed consent to participate in this trial.

Exclusion criteria

Exclusion criteria: ASA grade IV; 1.history of epilepsy; 2.long-term benzodiazepines history;3.myasthenia gravis schizophrenia or Parkinson's disease; 4.cognitive disorder or hearing disorder; 5. BMI?32 kg/m; 6.drunk or drug allergy;7.severe hepatic dysfunction (Child-Pugh class C) severe renal dysfunction;8.benzodiazepines or propofol allergic history;9. left atrial or left atrial appendage thrombus; 10.pregnant; 11.attend other medcine in 3 months.

Design outcomes

Primary

MeasureTime frame
sedation recovery time;

Secondary

MeasureTime frame
hypotension;hypoxemia;sedation induction time;

Countries

China

Contacts

Public ContactHuang Xinmiao

Department of Cardiovasology,Changhai Hospital,Naval Medical UniversityShanghai

18883922985@163.com+86 135 8558 8854

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026