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Study on neurometabolism in the pontine region of patients with diffuse axonal injury based on magnetic resonance spectroscopy

Study on neurometabolism in the pontine region of patients with diffuse axonal injury based on magnetic resonance spectroscopy

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2500095494
Enrollment
Unknown
Registered
2025-01-08
Start date
2025-01-10
Completion date
Unknown
Last updated
2025-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Diffuse axonal injury

Interventions

Control group:None
TBI group:None

Sponsors

Haining People's Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 60 Years

Inclusion criteria

Inclusion criteria: 1.Trauma patients admitted within 6 hours of injury; 2.Age 18 - 60 years old, male or female; 3.Magnetic resonance DWI and spectral imaging can be completed within 7 days after injury; 4.Patients and their families informed consent and volunteered to participate in the study.

Exclusion criteria

Exclusion criteria: 1.Respiratory and circulation instability caused by severe multiple injuries; 2.Previous cerebrovascular disease, central nervous system damage, seizures and intracranial space-occupying lesions; 3.Previous history of mental illness or congenital mental impairment and other reasons cannot cooperate with the assessment.

Design outcomes

Primary

MeasureTime frame
N-acetylaspartate;—

Secondary

MeasureTime frame
Creatine;Choline;cognitive evaluation;—

Countries

China

Contacts

Public ContactWeiliang Chen

Haining people's hospital

497425408@qq.com+86 15888334168

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026