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Comparison of ciprofol–nalbuphine and propofol–nalbuphine sedation during painless gastroenteroscopy: A prospective, double-blind, randomised, controlled trial

Comparison of ciprofol–nalbuphine and propofol–nalbuphine sedation during painless gastroenteroscopy: A prospective, double-blind, randomised, controlled trial

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500095492
Enrollment
Unknown
Registered
2025-01-08
Start date
2025-01-10
Completion date
Unknown
Last updated
2025-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Gastrointestinal disease

Interventions

NC Group:Ciprofol intravenous injection
NP Group:Propofol intravenous injection

Sponsors

Wuxi Huishan District, People's Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1. Subjects are voluntary and sign the informed consent form for this trial 2. Age greater than or equal to 18 years old and less than 65 years old, ASA score of grade I or II .3 SPO2>=92% when breathing air before surgery; 180mmg>=SBP>=90mmHg; 100>=DBP>=50mmHg; 18kg/m2<=BMI<=28kg/m2 4. Voluntarily undergo painless colonoscopy

Exclusion criteria

Exclusion criteria: 1. History of propofol, cyclopofol, nalbuphine allergy 2. History of mental illness and drug abuse 3. Cardiopulmonary function (severe hypertension, myocardial ischemia, heart failure, second-degree atrioventricular block, severe COPD, etc.) 4. History of hyperthyroidism 5. History of cardiopulmonary disease and cranial surgery 6. Abnormal liver and kidney function 7. History of long-term opioid use, sedative and analgesic drug abuse 8. Those who cannot be selected for any reason in the opinion of the investigator

Design outcomes

Primary

MeasureTime frame
Incidence of intraoperative adverse events;

Secondary

MeasureTime frame
Anesthesia recovery time;

Countries

Chinna

Contacts

Public ContactYu Zhiyang

Wuxi Huishan District, People's Hospital

yuzhiyang2020@sohu.com+86 510 8331 8200

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026