The main symptoms of chronic obstructive pulmonary disease are chronic cough, sputum production, chest tightness, shortness of breath, and difficulty breathing.
Conditions
Interventions
CF6 low-level group:None
CF6 high-level group:None
Sponsors
Xi'an Jiaotong University Second Affiliated Hospital
Eligibility
Sex/Gender
All
Age
40 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1.Complies with COPD diagnosis: Patients are diagnosed according to the GOLD 2024 guidelines, with the standard being that the ratio of forced expiratory volume to forced vital capacity in the first second after inhaling bronchodilators is less than 70%; 2.Diagnostic criteria for pulmonary hypertension: Referring to the 2009 European Heart Association/European Respiratory Association Guidelines for the Diagnosis and Treatment of Pulmonary Hypertension and the 2018 British Society of Echocardiography Guidelines, pulmonary artery systolic pressure is calculated based on the detection of tricuspid regurgitation velocity and valve pressure difference using echocardiography. A value of >= 35 mmHg is considered to have pulmonary hypertension; 3.Age >= 40 years old but < 80 years old; 4.Patients who have completed chest CT, lung function examination, cardiac ultrasound, blood routine, biochemical examination, and blood CF6; 5.The patient has reading and writing abilities and no communication barriers.
Exclusion criteria
Exclusion criteria: 1.Patients with the following respiratory system diseases: active pulmonary tuberculosis, bronchial asthma, and bronchiectasis; 2.Patients with severe complications including liver and kidney dysfunction; 3.Patients with combined acute coronary syndrome, malignant arrhythmia, and left heart failure; 4.Merge malignant tumor patients; 5.Patients with combined connective tissue disease; 6.Those who have undergone major surgical procedures in the past month; 7.Patients with language or cognitive impairments; 8.Patients who refuse to undergo chest CT, lung function tests, blood routine, and biochemical tests.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The incidence of COPD combined with PH;Number of acute exacerbations of COPD in one year; | — |
Secondary
| Measure | Time frame |
|---|---|
| Number of hospitalizations per year for COPD patients;One year mortality rate of COPD patients; | — |
Countries
China
Contacts
Public ContactMing Zhang
Xi'an Jiaotong University Second Affiliated Hospital
Outcome results
None listed