Catheter ablation of atrial fibrillation
Conditions
Interventions
CP group:Cyclopropofol 0.2mg/kg+ alfentanil 3ug/kg was used for induction, followed by continuous pumping of cyclopropofol 1mg/kg/h until the end of surgery
P group:Induction was performed with propofol 1mg/kg+ alfentanil 3ug/kg, followed by propofol 4mg/kg/h continuous pump infusion until the end of surgery
Sponsors
Heze Municipal Hospital
Eligibility
Sex/Gender
All
Age
38 Years to 58 Years
Inclusion criteria
Inclusion criteria: (1) for patients with symptomatic paroxysmal atrial fibrillation, persistent atrial fibrillation, or recurrent atrial fibrillation refractory to or intolerant of class I or class III antiarrhythmic drugs (all assessed by professional cardiologists, patients with radiofrequency ablation indications); (2) patients undergoing radiofrequency ablation for the first time (3) age of 18-65 years old (4) ASA grade I-II (5) BMI< 35 kg/m^2
Exclusion criteria
Exclusion criteria: (1) patients with recent repeated use of narcotic analgesics and opioid tolerance (2) myocardial infarction, ventricular dysfunction, coronary artery dysfunction; Complicated with serious bradyarrhythmias, such as sick sinus syndrome, III degree atrioventricular block (3) Severe pulmonary disease, severe anemia or thrombocytopenia, untreated hyperthyroidism, and severe hepatic and renal insufficiency (4) patients with vertigo and headache (5) patients with central nervous system (CNS) diseases, CNS stimulant drugs or respiratory defects; Patients with brain injury and increased intracranial pressure (6) drinking history within one week (7) patients with a history of mental disorders and epilepsy (8) patients allergic to study drugs and anticoagulant drugs (9) unable to communicate effectively with patients
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Invasive blood pressure;Heart rate;Oxygen saturation of the pulse;BIS index; | — |
Secondary
| Measure | Time frame |
|---|---|
| The dose of alfentanil was added during the operation;Time of awakening after operation; | — |
Countries
China
Contacts
Public ContactWenyu Zhao
No. 2888 Caozhou Road, Mudan District, Heze City
Outcome results
None listed