Atopic dermatitis
Conditions
Interventions
Study Group:Take Clostridium Typhimurium Live Bacteria Capsules 3 capsules twice daily
Control group:Take placebo capsules 3 capsules twice a day
Sponsors
Tianjin Medical University General Hospital
Eligibility
Sex/Gender
All
Age
7 Years to 65 Years
Inclusion criteria
Inclusion criteria: (1)Patients who meet Hanfin & Rajka diagnostic criteria and have a score of 10 <= SCORAD <= 50 at screening. (2) Aged 7 to 65 years old, male and female. (3) Subjects or guardians sign an informed consent and commit to cooperating with the study for the entire duration of the experiment.
Exclusion criteria
Exclusion criteria: (1)Patients who refuse to sign an informed consent form, or have a poor likelihood of follow-up. (2) Pregnancy or breastfreeding. (3) Patients with severe immunodeficiency diseases, serious infections, cancer or other serious illnesses. (4) The presence of other skin diseases that may interfere with the efficacy evaluation. (5) Use of probiotics, systemic corticosteroids, immunosuppressive, biologics, etc. in the 4 weeks prior to the trial. (6) Patients who have a habit of using probiotic products (yogurt, probiotic drinks, etc.) (7) Patients who are allergic or intolerant to the components of the test probiotic medication.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| SCORAD at 8 weeks; | — |
Secondary
| Measure | Time frame |
|---|---|
| SCORAD,DLQI,POEM at 4, and 8 weeks;serum inflammatory factor at 0 and 8 weeks;Intestinal Flora at 0 and 8 weeks; | — |
Countries
China
Contacts
Public ContactHuiping Wang
Tianjin Medical University General Hospital
Outcome results
None listed