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Correlation analysis of gut microbiota/adrenaline metabolism pathway /ADRB2 with various tumors - Retrospective cohort study

Correlation analysis of gut microbiota/adrenaline metabolism pathway /ADRB2 with various tumors - Retrospective cohort study

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2500095422
Enrollment
Unknown
Registered
2025-01-07
Start date
2025-01-16
Completion date
Unknown
Last updated
2025-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

tumors

Interventions

Sponsors

Zhujiang Hospital of Southern Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: Case inclusion criteria: 1. Individuals diagnosed for the first time with colorectal cancer, breast cancer, liver cancer or non-small cell lung cancer by pathological biopsy; 2. Agree to join the study and sign the informed consent. Health control inclusion criteria: 1. Healthy people with no obvious diseases and normal physical examination report; 2. Matched age and sex with case group.

Exclusion criteria

Exclusion criteria: 1. Major chronic diseases, such as hypertension, diabetes, chronic kidney disease and blood system diseases in recent years; 2. Have taken laxatives or had a colonoscopy within 1 week prior to sample collection; 3. Have taken drugs, probiotics, antibiotics for colorectal diseases within 1 month before the collection of samples; 4. Received surgical treatment within 3 months prior to sample collection; 5. Anti-tumor therapy was performed before sample collection; 6. Samples with incomplete information and untraceable samples.

Design outcomes

Primary

MeasureTime frame
Gut microbiota (mainly bifidobacterium);Monoamine oxidase;Epinephrine;adrenergic receptor beta 2 ;

Secondary

MeasureTime frame
cyclic guanosine monophosphate;protein kinases G;

Countries

China

Contacts

Public ContactHongwei Zhou

Zhujiang Hospital of Southern Medical University

biodegradation@gmail.com+86 186 8848 9622

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026