Acute Respiratory Failure
Conditions
Interventions
Quick Reduction Flow Group:Directly reduce HFNC flow rate from 40 L/min to 20 L/min
Gradual Decrease Flow Group:Reduce the HFNC flow rate by 5 L/min per hour.
Sponsors
Suzhou Hospital of Anhui Medical University (Suzhou Municipal Hospital of Anhui Province)
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Age >=18 years old; 2. Patients with acute hypoxic respiratory failure; Stay in intensive care unit (ICU) for >=72 hours; 3. 4. Informed consent has been obtained.
Exclusion criteria
Exclusion criteria: 1. End-stage maintenance patients; Patients with acute heart failure; 2. 3. Acute exacerbation of chronic obstructive pulmonary disease with type II respiratory failure; 4. Sequential treatment of patients after mechanical ventilation; 5. Other patients who do not meet the indications for HFNC.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Duration of HFNC application;ICU length of stay (LOS);Length of stay in hospital;Primary clinical outcomes; | — |
Secondary
| Measure | Time frame |
|---|---|
| Heart rate;Blood pressure;Respiratory rate;Peripheral capillary oxygen saturation;Fraction of Inspired Oxygen;Arterial oxygen partial pressure;Arterial carbon dioxide partial pressure; | — |
Countries
China
Contacts
Public ContactYaguang Wu
Suzhou Hospital of Anhui Medical University (Suzhou Municipal Hospital of Anhui Province)
Outcome results
None listed