Skip to content

The effect of methylene blue on chronic postsurgical pain in thoracoscopic patients undergoing serratus anterior plane block: a prospective, randomized, double-blind controlled trial

The effect of methylene blue on chronic postsurgical pain in thoracoscopic patients undergoing serratus anterior plane block: a prospective, randomized, double-blind controlled trial

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500095401
Enrollment
Unknown
Registered
2025-01-07
Start date
2025-01-10
Completion date
Unknown
Last updated
2025-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

chronic postsurgical pain

Interventions

M+R group:Ultrasound guided anterior serratus muscle plane block using 0.25% ropivacaine injection combined with 0.1% methylene blue injection 30ml
R group:Ultrasound guided anterior serratus muscle plane block with 30ml of 0.25% ropivacaine injection

Sponsors

Jinniu District People's Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: (1) Patients undergoing thoracoscopic lung surgery; (2) Age >= 18 years old; (3) American Society of Anesthesiologists (ASA) classification: Grade I-III.

Exclusion criteria

Exclusion criteria: (1) Patients with severe heart and lung dysfunction who are intolerant to surgery; (2) The patient has a history of drug allergies to ropivacaine or methylene blue; (3) History of previous mental illness and chronic pain disorders; (4) Patients with preoperative cognitive impairment; (5) There are contraindications for nerve block.

Design outcomes

Primary

MeasureTime frame
NRS score 6 months after surgery;

Secondary

MeasureTime frame
NRS scores at 1 day before surgery, 24 hours after surgery, 1 month after surgery, and 3 months after surgery;BPI Brief Pain Scale Score ;SF-36 scale scores ;DN4 scale scores ;Patient pain trajectory;Adverse reaction incidence rate;

Countries

China

Contacts

Public ContactDezhou Jiang

Jinniu District People's Hospital, Chengdu

809130221@qq.com+86 158 9221 5042

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026