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The Impact of Oxycodone on the Quality of Postoperative Recovery in Obese Patients Undergoing Laparoscopic Bariatric Surgery

The Impact of Oxycodone on the Quality of Postoperative Recovery in Obese Patients Undergoing Laparoscopic Bariatric Surgery

Status
Recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500095380
Enrollment
Unknown
Registered
2025-01-07
Start date
2025-01-07
Completion date
Unknown
Last updated
2025-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

laparoscopic bariatric surgery

Interventions

Oxycodone group:Induction: intravenous injection of oxycodone 0.3 mg/kg
Skin closure: intravenous injection of oxycodone 0.1 mg/kg.
Sufentanil group:Induction: intravenous injection of sufentanil 0.3 µg/kg
Skin closure: intravenous injection of sufentanil 0.1 µg/kg.

Sponsors

Affiliated Hospital of Xuzhou Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 60 Years

Inclusion criteria

Inclusion criteria: 1.Aged 18 to 60 years, regardless of gender;2.ASA classification II-III;3.Body mass index (BMI) >= 30 kg/m²;4.Patients scheduled for elective laparoscopic bariatric surgery.

Exclusion criteria

Exclusion criteria: 1.Individuals with severe cardiovascular diseases or liver/kidney dysfunction;2.Individuals with a history of open abdominal surgery;3.Individuals with a history of psychiatric disorders;4.Individuals with long-term opioid use;5.Individuals with chronic alcohol abuse;6.Individuals allergic to the study medication;7.Individuals unable to understand the rating scales or who refuse to participate;8.Individuals with severe obstructive sleep apnea hypoventilation syndrome.

Design outcomes

Primary

MeasureTime frame
recovery quality;

Secondary

MeasureTime frame
pain;Recovery time;Incidence of nausea and vomiting.;Incidence of hypoxemia;Rescue analgesia rate;time of first exhaust;

Countries

China

Contacts

Public ContactHao Jiao

Medical Ethics Committee of the Affiliated Hospital of Xuzhou Medical University

jiaohaoyishi@163.com+86 181 6877 7312

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026