Caries disease
Conditions
Interventions
Pediatric caries filling treatment + Placebo group:placebo
Oral Health Children's Group:N/A
Children's caries filling treatment + probiotic mouthwash group:Use a postbiotic-containing mouthwash
Sponsors
Affiliated Stomatological Hospital of Nanchang University
Eligibility
Sex/Gender
All
Age
6 Years to 12 Years
Inclusion criteria
Inclusion criteria: 1. Age 6-12 years old, in good health; 2.high caries susceptibility activity and no periodontal disease; 3.Good daily oral hygiene habits, brush teeth once a day in the morning and once in the evening; 4.Good general health, no history of long-term drug use, no recent use of antibiotics, and no participation in other projects; 5.The compliance was good, the parents of the children fully understood the test, did not use any oral care products other than the mouthwash provided (including antibiotic mouthwash, antibacterial toothpaste, xylitol chewing gum, etc.), ensured that the diet balance during the test was consistent with the daily life, and voluntarily signed the informed consent form;
Exclusion criteria
Exclusion criteria: 1. Any familial hereditary disease or serious systemic disease that may interfere with the results of the study. 2.Taking antibiotics within 1 month, hormones and immunosuppressants within 6 months; 3.Those who have been using postbiotic products for a long time, like to chew xylitol chewing gum every day, and are allergic to postbiotic mouthwash; 4. Wearing appliances, or endodontic treatment, or enamel hypoplasia that can be distinguished by the naked eye; Clinically significant lesions of the oral mucosa, such as thrush, herpetic stomatitis, bacterial stomatitis, traumatic ulcers, geographic tongue, angular cheilitis, and chronic cheilitis; 5. Life history in high-fluoride areas.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Acid production capacity test of plaque; Salivary buffering capacity test; | — |
Secondary
| Measure | Time frame |
|---|---|
| Secondary caries and new caries; | — |
Countries
China
Contacts
Public ContactLiu Qing
Affiliated Stomatological Hospital of Nanchang University
Outcome results
None listed