None
Conditions
Interventions
control group:Postoperative self-controlled intravenous analgesia with sufentanil 1.5 µg/kg
Observation Group:Postoperative self-controlled intravenous analgesia with oxybutynin 0.35 mg/kg
Sponsors
Hangzhou First People's Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: (1) Patients undergoing elective laparoscopic gastric cancer surgery in our hospital from November 2024 to November 2025 were selected as clinical trial subjects; (2) 1 h <= expected duration of surgery <= 4 h; (3) no gender restriction; (4) age 18-65 years old; (5) 18 kg/m^2 <= body mass index (BMI) <= 29 kg/m^2; (6) ASA classification ?-?.
Exclusion criteria
Exclusion criteria: (1) the presence of pulmonary infection; (2) the presence of severe damage to target organs such as liver, kidney, heart, brain, etc.; (3) a history of difficult airway disease; (4) a known history of allergy to any component of the test drug or allergy to or contraindication to anaesthesia/analgesic medications used in the study; (5) the use of medications affecting the efficacy of postoperative analgesia, such as non-steroidal analgesic drugs, 1 day prior to randomisation.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Time of first postoperative defecation; | — |
Secondary
| Measure | Time frame |
|---|---|
| The pain (VAS) and sedation (RASS) scores of the patients immediately after awakening from surgery, at 2 hours, 6 hours, 12 hours, 24 hours, and 48 hours postoperatively.;Number of PCA single doses;Effective compression rate of intravenous self-controlled analgesic pumps in patients at 48 hours postoperatively (effective number of compressions/total number of compressions);Number of remedial analgesia;Number of remedial antiemetic sessions;Adverse reactions (dizziness, respiratory depression, nausea and vomiting, itching, urinary retention, etc.) within 48 hours after surgery;Postoperative gastrointestinal function I-FEED score (intake, nausea, vomiting and duration of symptoms);Time of first bowel movement;First time out of bed after surgery;Time of first postoperative meal;hospital fees;Length of hospitalization; | — |
Countries
Chian
Contacts
Public ContactYaqin Huang
Hangzhou First People's Hospital
Outcome results
None listed